Search on: ALZHEIMER DISEASE 
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Descriptor English:   Alzheimer Disease 
Descriptor Spanish:   Enfermedad de Alzheimer 
Descriptor Portuguese:   Doença de Alzheimer 
Synonyms English:   Dementia, Senile
Acute Confusional Senile Dementia
Dementia, Alzheimer Type
Presenile Alzheimer Dementia
Senile Dementia, Alzheimer Type  
Tree Number:   C10.228.140.380.100
C10.574.945.249
F03.087.400.100
Definition English:   A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) 
See Related English:   Amyloid beta-Protein
Amyloid beta-Protein Precursor
Aphasia, Primary Progressive
Cerebral Amyloid Angiopathy
Kluver-Bucy Syndrome
Neurofilament Proteins
tau Proteins
 
History Note English:   1998(1963); for DEMENTIA, PRESENILE and DEMENTIA, PRIMARY DEGENERATIVE SENILE use DEMENTIA 1981-1999; for DEMENTIA SENILE use DEMENTIA 1966-1999 
Allowable Qualifiers English:  
blood cerebrospinal fluid
chemically induced classification
congenital complications
diet therapy diagnosis
drug therapy economics
ethnology embryology
enzymology epidemiology
etiology genetics
history immunology
metabolism microbiology
mortality nursing
pathology prevention & control
physiopathology parasitology
psychology radiography
rehabilitation radionuclide imaging
radiotherapy surgery
therapy urine
ultrasonography veterinary
virology  
Record Number:   545 
Unique Identifier:   D000544 

Occurrence in VHL:
 

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